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Conversely, the metabolic journey of Treg cells carves a distinctive trail, with AMPK reigning as the chief metabolic maestro ( In T cells, the mTOR signaling axis serves as a regulatory hub, influencing various cellular mechanisms such as proliferation, programmed cell death, differentiation, and metabolic processes via activation of downstream transcriptional elements

doi: 10.1016/j.celrep.2019.06.010 194 JunJCRathoreAYounasHGilkesDPolotskyVY

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doi:10.1177/1941874415588319 Lippi G, Favaloro EJ