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As oxidative stress and neuroinflammatory pathways have considerable crosstalk (See Scheme 1), there is an unmet need for further research exploring this relationship in the pathophysiology of epilepsy

Corticosteroids as monotherapy as first-line treatment (186 patients, 13 studies) provided an ORR of 47% (95% confidence interval [CI], 34-60)

Among them, the Fe-S cluster assembly scaffold protein ISCU2 relies on six other core ISC (Iron-Sulfur Cluster assembly) proteins: the cysteine desulfurase complex NFS1ISD11ACP1, frataxin (FXN), ferredoxin (FDX2), and its reductase (FDXR), to construct the [2Fe-2S] center

GOx was used as an enzymatic label that was conjugated to the GAPDH protein through glutaraldehyde cross-linking 17

Its particularly effective at raising intracellular glutathione levels and is widely used to support liver health and detoxification