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[21] [22] [23] [24] [25] Anemia may present with a number of further common symptoms, [21] [26] including hair thinning and loss, early greying of the hair, mouth ulcers, bleeding gums, [22] angular cheilitis, a look of exhaustion with pale and dehydrated or cracked lips and dark circles around the eyes, as well as brittle nails

Animal Model:NMRI-Hannover (male, 30 g, deep partial skin thickness burns induced by 5 s direct flame exposure covering 20% total body area) [2] Dosage:i.p.: 10 ng/kg, 10 g/kg

When the gut environment is calm, vagal tone improves, shifting the autonomic nervous system away from the hyper-aroused "fight or flight" sympathetic state and toward the restorative "rest and digest" parasympathetic state

The default works for most peptides but not all

Patients who cannot tolerate oral iron supplements or for whom they have proven ineffective