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A 2012 study published in Journal of Pharmacology and Experimental Therapeutics demonstrated that a seven-day dihexa dosing protocol produced cognitive improvements in rodent models that persisted for at least 30 days post-treatment, despite the compound being undetectable in plasma within 12 hours of the final dose

An optimally functioning homocysteine pathway provides methyl and sulfur groups for biochemical reactions such as detoxification, healthy immune function, ideal joint and cartilage structure, and brain and cardiovascular health so its important to metabolize homocysteine effectively

doi: 10.3390/ijms17111809

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Glucagon enhances HMGCS2 enzyme activity by decreasing the levels of succinyl-CoA (Quant et al., 1990)