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Drug-Induced Orthostatic Hypotension When orthostatic hypotension is documented as caused by medication, you need three codes: I95.2 (Hypotension due to drugs) primary diagnosis T code(s) for the specific medication(s) with 5th/6th character 5 (adverse effect) R55 (Syncope and collapse) if loss of consciousness occurred Common medications causing orthostatic hypotension include: Antihypertensives (ACE inhibitors, ARBs, calcium channel blockers, beta blockers) Diuretics Alpha blockers (often used for BPH) Antidepressants (especially TCAs) Antipsychotics Parkinson's medications (levodopa) Nitrates Critical coding note: I95.2 specifically states "Hypotension due to drugs" in the excludes note

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STAT3 activity promotes the BCSC phenotype by upregulating the expression of the pluripotency factor KLF4