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Lack of glucagon receptor signaling and its implications beyond glucose homeostasis

-Sitosterol selectively inhibits the activity of the pro-inflammatory mediator COX-2 and reduces the levels of the oncogenic PGE 2 in tumor tissues, blocking the promotion of tumor cell proliferation by the COX-2/PGE 2 inflammatory axis (92)

[DOI] [PMC free article] [PubMed] [Google Scholar] 261.Mc Carthy D.J., Malhotra M., OMahony A.M., Cryan J.F., ODriscoll C.M

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Experimental studies in diabetic rats demonstrate that ALA (100350 mg/kg/day) improves nerve blood flow (NBF), vascular relaxation, and motor nerve conduction velocity while reducing oxidative markers like thiobarbituric acid reactive substances (TBARS) [76]