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Total RNA was purified using the Promega ReliaPrep RNA Tissue Miniprep kit (z6112)

After 4 weeks, L-glutamine decreased HbA1c and fructosamine irrespective of sitagliptin in patients with T2DM, and postprandial glucose decreased with significant time-treatment interactions, while HbA1c and fructosamine decreased without significant time-treatment interactions [38]