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Similarly, people with anxiety who drink heavily may experience stressful emotions that can cause a change in the stomachs enzymes, which affects how a person breaks down alcohol

After verifying oxidizing influences on Mia40 in vivo , we next wanted to test which reducing pathways act on Mia40 or more specifically whether the redox state of Mia40 is susceptible to changes in E GSH (Figure 8A)

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Importantly, this regulation cascade can be exploited by targeting YBX1 to block AMPK protein synthesis and targeting GLUT1 to induce energy stress, which synergistically blunts tumor growth in vivo