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The mRNA levels of key genes in these pathways, such as Spp1, AP-1, TLR2, Ccl4, IL1b, Scd1 , and Lepr , were significantly different in caffeine-treated mice and HFHC mice (Figures 8D,E)

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pylori ) is a well-documented driver of gastric cancer through its ability to induce chronic gastritis and -catenin signalling [30]

Generation and characterization of iPSC-derived liver organoids (LOs) from BC patient 1 and healthy controls for drug metabolism To generate NOCS-compatible LOs from normal and patient iPSCs, we applied our protocols established based on the liver developmental process 28 (Fig