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Furthermore, when glutamine catabolism is inactivated, tumor cells can produce glutamate via asparagine synthetase ( ASNS )-mediated glutamine, which in turn can generate ATP, thereby inhibiting the AMPK pathway and completely activating mTORC1 on the lysosomal surface, a process primarily mediated by the mTORC1 coactivator Rheb [144]

Concurrent vitamin D supplementation and exercise training improve cardiac fibrosis via TGF-/Smad signaling in myocardial infarction model of rats

Electronic Journal of Biotechnology

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Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammationMediating treatment options (Review)