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Caspase and apoptosis pathways become activated through upregulation of CASP1, CASP3, CASP6, CASP7, CASP8, and CASP10 genes

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While cognitive resilience is an emerging research domain, the mechanisms driving cognitive frailty (chronic cognitive decline in absence of measurable neuropathology) are less well described

doi: 10.1016/j.ejphar.2005.02.033