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Diagnosis and management of iron deficiency anemia in inflammatory bowel disease

Important: These findings are promising, but high-quality human trials remain limited

Extensive work has implicated reactive oxygen species (ROS) derived from metal-catalyzed oxidation in lipid, protein, and DNA oxidation (Yoshida et al., 1993

the accumulation of reactive oxygen species (ROS) including superoxide and hydrogen peroxide, which results in lipid peroxidation and development of visible necrotic lesions (hypersensitive response, HR) ( via thiol-disulfide redox reactions ( GSH1 ) encoding -glutamyl-cysteine synthase ( PR-1 and enhanced resistance to bacterial and fungal pathogens