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Consequently, these changes lead to increased oxidative stress, insulin resistance, inflammation, pancreatic -cell dysfunction with apoptosis, and eventually diabetic complications, including retinopathy, neuropathy, cardiomyopathy, microvascular complications, and nephropathy 47,48,49,50

In fact many lifestyle choices can decrease B12 levels such as: Excessive alcohol consumption Stress Birth control pills And pre existing conditions like kidney and liver issues

In line with the qRTPCR results, NaOX significantly reduced the protein abundance of CPT1 (Fig

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