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We observed partial inhibition of the autophagic flux in still asymptomatic 6-week-old Alms1 -/- mice, as well as signs of a more complete blockade in diseased 20-week-old Alms1 -/- animals

Nat Rev Cancer 2013

Ricciolini, M.E

Research has shown that high fructose diets are at greater risk for kidney stone formation (2, 3, 4) Soft drinks with phosphoric acid significantly increase calcium excretion and kidney stone formation (5)

Importantly, clinical observations have shown that elevated plasma free fatty acids, increased lipid intermediates, and markers of oxidative stress are associated with adverse outcomes in HF patients, emphasizing the translational significance of this interplay