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Description

SS-31 (Elamipretide) A mitochondria-targeting tetrapeptide that binds cardiolipin in the inner mitochondrial membrane, improving electron transport chain efficiency, ATP production, and ROS handling

Using a panel of 13 ALL cell lines (6 B-cell precursors and 7 T-cell ALL precursors) and untargeted hydrogen nuclear magnetic resonance ( 1 H-NMR)-based metabolomics, we characterized MTX-triggered metabolic disturbance in detail