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(Note: Methylcobalamin is the preferred form of B12 for supplementation versus cyanocobalamin, which is a synthetic form.) For the study, methylcobalamin was administered daily at 500 g (.5 mg) dose to 25 autistic children and young adults during a 200-day period with positive results

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The standard NHS regimen for treating deficiency involves loading doses followed by maintenance therapy, with frequency determined by the underlying cause and severity of deficiency

Am J Physiol, 1978