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doi: 10.1016/j.neuropharm.2018.07.001

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Record: When the pain started Which dose you were taking When you last administered the medication Which joints or muscles are affected Whether the area is swollen, warm, or red Whether activity makes the pain better or worse Whether symptoms return after each weekly dose Also consider recent changes in exercise, hydration, eating patterns, sleep, footwear, and daily activity

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Ultimately, these things are variable and come down to what youre eating, hydration status, medications and certain conditions, concludes Ramesh