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10.1093/rheumatology/kez338 Rheumatology (Oxford)

Gene expression profiles from subcutaneous and visceral adipose tissues of severely obese individuals were retrieved (GEO accession number: GSE22070 [73]

Cushingoid features, growth retardation, increased risk for infections), and suppression of the hypothalamic-pituitary-adrenal (HPA) axis, which can result in an adrenal crisis if doses are not carefully tapered after a patient has been on systemic steroids for more than 15 days (Aljebab et al, 2017)

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