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Reducing that inflammation while stimulating collagen production produces a dual benefit that microneedling alone cannot achieve

Mitochondria continuously undergo fission and fusion, and increased fission has been correlated with liver injury

Moreover, the gut microbiota and its associated metabolites promote the differentiation and function of anti-inflammatory macrophages, Treg cells, CD4 + CD8 + regulatory cells, IL-10 + and/or IL-35 + B regulatory cells, as well as IL-22-producing innate lymphoid cells 3 (ILC3), which are involved in maintaining the gut mucosal homeostasis (Su et al., 2022) and protecting the kidneys (Su et al., 2022)

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Mitochondrial dynamics is identified as the fusion and fission of mitochondria (Fig