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Mouse-study observations In the Billon 2023 and Billon 2024 studies, mice dosed at 25-50 mg/kg IP for up to 28 days showed no overt toxicity, no sickness-related weight loss, no liver-enzyme signal at the doses tested, and no cardiac dysfunction

The results suggested that low doses of aflatoxin were both more toxic and more carcinogenic to monkeys fed low-protein diets

Furthermore, hypoxic conditions (1% O 2 ) suppressed the cytotoxicity of vitamin C more in 60 cancer cell lines than normoxic conditions (21% O 2 ) did 23

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