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And 5-amino-1mq is the compound that researchers have developed specifically to shut it down

It is also indirectly responsible for cystine uptake via the cystine/glutamate antiporter system that reduces to cysteine, another rate-limiting precursor in glutathione synthesis [12]

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The sections were thaw-mounted onto glass slides coated with indium tin oxide (VisionTek Systems)

COL3A1 testing identified the Glu682Lys variant (identical pathogenic variant to family 1 and family 4), which was subsequently identified in the father (IV.1) and another daughter (V.3)