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a combination of 1 mM IBMX, 1 M dexamethasone, and 10 g/ml of insulin in media were added to fully confluent 3T3-L1 fibroblasts for three days (days 0-3) to initiate differentiation

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sulfonate e.g., trifluoromethanesulfonate, mesylate, tosylate, besylate, and the like halide e.g., fluor Another aspect of the invention pertains generally to the use of the cations of the invention to inhibit NNMT and diseases or conditions involving NNMT