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Third, TMAO may potentially disrupt the equilibrium of renal electrolytes and water transport by inhibiting sodium and water reabsorption in the kidneys, resulting in sodium retention and volume expansion, characteristic features of chronic kidney disease ( Figure 4 Besides, TMAO may directly harms kidney structure, causing glomerular hypertrophy, tubulointerstitial fibrosis, and renal inflammation in animals, which promoting the progression of CKD

Nat Cell Biol 20:11811192 Zheng J, Conrad M (2020) The metabolic underpinnings of ferroptosis

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Its just that all these ordinary things were happening in an extraordinary place. Hong Kong: Insider Travel Guide An ingenious community The complexity of the Walled City also fascinated local architect Aaron Tan, now the director of Hong Kong firm Research Architecture Design