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The medication is commonly used alongside metformin, with the combination often providing complementary mechanisms of action for improved glycemic control

Across this body of research, no significant toxicity has been reported at doses ranging from 1 g/kg to 10 mg/kg in rodent models

Lower levels of IGF-1 in the blood are known to be associated with an increased risk of breaking a bone

Notably, newborn infants are at risk of severe toxicity (as discussed in Contraindications), but in adults and older children, the small benzyl alcohol dose is very well tolerated