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An important component of -glucans in Pleurotus sajor-caju helps to protect from oxidative stress and obesity in obese mice by the action mechanism of bioactive components, which involves in inhibition of adipocytes and lipolysis

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Challenges in the therapy of NeuroHIV As ART alone is insufficient to fully suppress HIV-1 replication, including the transcription and translation of HIV-1 provirus in both T-cell reservoirs and non-CD4 T-cell reservoirs, there is a critical need to develop new brain-penetrating agents that can effectively target both CNS and peripheral immune cells to simultaneously silence HIV-1 and reduce the risk of neuroinflammation

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N Engl J Med (2012) 366(4):34859