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Mycolic acid methyltransferase (MmaA4) Compared with other SAM-MTs, the structures of apo-MmaA4 and MmaA4-SAM complex both contain a typical core SAM-MT fold [a central seven-stranded -sheet (3-2-1-4-5-7-6) with three helices flanking on each side] and several individual components [including an helical at the N-terminal, and a set of four antiparallel helical (2-5) between strands 6 and 7] (Fig

HIV infection and the gastrointestinal immune system

doi: 10.3390/life13071496 112 MadondoMTQuinnMPlebanskiM

45), which are involved in the biogenesis of the phagophore, that is, the open autophagosome precursor, cause human diseases

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