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ZhangJKZhangZGuoZAFuYChenXJChenWJet al

The cells were then treated with culture medium containing DOX, MND, ART, MND-ART, or MND-ART-GEL, with final concentrations of DOX and ART of 240 ng/mL and 1.92 g/mL, respectively

Grimm, J., Perez, J

Indeed, melatonin activates MPK3 and MPK6 via four MKKs (i.e., MKK4/5/7/9) (210), and MAPKKK 3 and OXI 1 (oxidative signal-inducible 1) kinases are responsible for triggering melatonin-induced defense signaling pathways (211)