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Abstract Major Depressive Disorder (MDD) is a highly prevalent and disabling psychiatric disorder, representing a major global health burden across all age groups

Finally, four records were included in our study: All four studies were included in the meta-analysis PRISMA figure (Fig

Results Symptomatic individuals had significantly elevated plasma PGA levels compared with both asymptomatic carriers and age-matched healthy controls, consistent with impaired GSH homeostasis

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Sowers, Jun Ren Pharmacology & Therapeutics.2018