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Glutathione quantification by HPLC Human and mouse brain specimens as well as pelleted CHO cells were homogenized in buffer containing 125 mM sucrose, 5 mM TRIS, 1.5 mM EDTA, 0.5% trifluoroacetic acid (TFA) and 0.5% mycophenolic acid (MPA) in mobile phase

Structural modifications such as the type and position of substituents and the degree of hydroxylation can directly influence the physicochemical properties, biological activities, and pharmacological profiles of different flavonoid subclasses (Zouaoui et al., 2021

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2,20 These inhibitors are orthosteric meaning that they bind at the active site