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Brain Fog and Cognitive Dysfunction: By crossing the blood-brain barrier, ALA reduces neuroinflammation and neutralizes oxidative stress within the central nervous system, supporting improved cerebral blood flow and helping to clear the cognitive haze associated with neuro-immune conditions

This reaction leads to the degradation of NAD and formation of the products adenosine diphosphate-ribose (ADPR) and nicotinamide ADP-rybosyl cyclase A reaction where NAD is converted to its cyclic analog cyclic-adenosine-diphosphate ribose (cADPR) and nicotinamide cADPR and ADPR cADPR and ADPR are second messengers involved in calcium signaling SIRTUINs NAD-dependent deacetylases involve don the control of metabolism, healthspan and aging

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Anthocyanin is believed to have the ability to scavenge free radical species like hydrogen peroxide, which can get elevated when mitochondrial dysfunction and glial inflammation occur, which here may be useful to reduce oxidative damage in neurodegenerative diseases

C., Georgantzi, S., Pintus, R., Fanos, V., & Malamitsi-Puchner, A