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If the distribution of confounding factors differs in the two arms, explicative regression analysis will be performed in which the dependent variable will be the normalisation of the serum vitamin B12 concentration, and the independent variable will be the treatment group

Regular follow-ups with progress tracking, lab monitoring of both anabolic and metabolic markers, and protocol adjustments to ensure safe, effective results

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It can be inferred that the structure of the microbial communities underwent noticeable changes when prolonged periods of HS were applied