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The Mechanisms of Basic Fibroblast Growth Factor in Tendon Healing The tendon healing process is subdivided into three chronological stages, which are integrated with each other and not independently separated: the inflammatory phase, the cell proliferation phase, and the remodeling phase (Yang et al., 2022)

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The slight acidity of the solution (pH approximately 3.04.0 at 0.1% concentration) protonates basic amino acid residues on poorly water-soluble peptides, increasing their net positive charge and improving electrostatic interaction with the surrounding aqueous solvent a mechanism that dramatically increases the solubility of many lyophilised peptide preparations that resist dissolution in neutral or alkaline aqueous conditions

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