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In particular, these cells highly express the monocarboxylate transporter MCT4 on their plasma membrane, which transports intracellularly accumulated lactate into the microenvironment, accelerating glycolytic flux [41, 42]

Apigenin-loaded galactose tailored PLGA nanoparticles: a possible strategy for liver targeting to treat hepatocellular carcinoma

With the advent of new technologies and a deeper understanding of neuronal metabolism, the field is poised for significant breakthroughs that could transform our approach to treating neurological disorders (Lee and Silva, 2009)

doi: 10.3390/pharmaceutics11010022

Once GSH is depleted, ROS and reactive nitrogen species escalate, leading to increased oxidative stress, mitochondrial dysfunction, and DNA damage