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Hemochromatosis is a genetic disorder that causes the body to absorb too much iron

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It is often advantageous to include an additional amino acid sequence which contains secretory or leader sequences, pro-sequences, sequences which aid in purification, such as multiple histidine residues, or an additional sequence for stability during recombinant production

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The aforementioned study demonstrated that Piezo1 channels are highly expressed during neuroinflammation in the central nervous system (CNS) and inhibit the release of pro-inflammatory cytokines