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F1000Res 4 , 1521 (2015)

Oxidative stress caused by factors such as environmental toxins, physical or emotional stress, strenuous exercise, and illness can lead to tissue damage, DNA damage, inflammation, neuro-degeneration and the development of chronic diseases such as cancer, diabetes, arthritis, stroke, cardiovascular disease, and more

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doi:10.1093/jnci/83.8.541

These include: Oxidative stress: One of the more recent studies on DSIP, from 2011, concluded that the peptide has a strong antioxidant effect owing to an ability to activate the (rat) bodys natural mechanisms against oxidative stress.21 Edema (swelling via fluid buildup): Again in rats, a 1992 study suggested that DSIP may have an antiedematic effect related to the activation of the GABAergic system and inhibition of serotonin, noradrenaline, and histamine systems.22 Convulsions: Two rodent studies in the 1990s support DSIPs use as an anticonvulsant