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However, ET-1 binds endothelial membrane ETB1 receptors, activating a signaling cascade leading to the production of NO and PGI2 and, finally, vascular relaxation (27)

A high coefficient indicates a lower amount of FAD in erythrocytes, i.e., a deficiency in vitamin B2

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4.2.5 Environmentally sustainable extraction techniques To minimize solvent consumption and maintain the sustainability of the environment, new approaches to extraction, like 1) supercritical fluid extraction (SFE) and 2) ultrasound-assisted extraction (UAE), are being explored ( 2 , offering a promising alternative to toxic organic solvents ( Table 4 )

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