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Recent studies showing the protective effect of the redox activity of PDI in cellular and zebrafish models of ALS have placed redox dysregulation centrally in ALS, implying that it has a much broader role than previously realized

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Clinical data showed that participants who skipped titration steps or escalated too quickly experienced nearly double the rate of gastrointestinal adverse events

Nevertheless, the influence on ion channels that affect cardiac contractility appears to be the main cardioprotective mechanism of H 2 S

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