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Other potentially attractive therapeutic strategies that could target the disrupted redox balance underlying halted reticulocyte maturation are amino-acid supplementation with L-glutamine, vitamin E supplementation, and NAC

La L-carnitina se sintetiza en el organismo a partir de los aminocidos lisina y metionina y se encuentra en altas concentraciones principalmente en tejidos que requieren gran cantidad de energa, como los msculos esquelticos

doi: 10.1016/j.cell.2012.11.022

Furthermore, age-related iron accumulation contributed to the tissue damage and pathologic manifestations of AD (Raven et al., 2013)

Taken together, the evidence suggests that lactate could exert differential effects depending on the metabolic status, cell type in which the effects of lactate are studied, and the pathological process analyzed