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Administration of high concentrations of sodium selenite preferentially targets and eradicates cancer cells because more free radicals are produced than in normal cells and no systemic selenotoxicity is produced (130)

Kong YX, Li ZS, Liu YB, Pan B, Fu X, Xiao R, et al

ROS oxidizing effects on proteins include protein carbonylation, the most well-documented form of protein oxidation, whereby protein side chains are targeted, resulting in loss of protein functions 84