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This evidence for lesion heterogeneity is important, as it emphasizes that different lesions may require different treatment strategies to enhance remyelination in some, promoting differentiation may suffice, whereas in others, increasing aOPC numbers will be required

Indeed, in our more that ten-year experience on thiols measurements in various cells and tissues 11,12,13,14,15 , the concentration of GSH has been often well below 1 mM, and comparable to that of Cys (Fig

Proline metabolism and cancer: emerging links to glutamine and collagen

There are also specific alterations in T cell subsets associated with aging

Glutathione: in defence of the lung