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Aging Dis 9(4):605 Rehman IU, Khan A, Ahmad R, Choe K, Park HY, Lee HJ et al (2022) Neuroprotective effects of nicotinamide against MPTP-induced Parkinsons disease in mice: impact on oxidative stress, neuroinflammation, Nrf2/HO-1 and TLR4 signaling pathways

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This could indicate higher than normal levels of oxidative stress in virus-infected SA-deficient tobacco cells in later stages of pathogenesis (5 days after inoculation, DAI) when necrotic (HR) lesions are fully developed, even if glutathione accumulation and TMV resistance is comparable to that of wild type plants

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