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Lactylation at the K247 residue of XRCC1 promotes its nuclear translocation and significantly enhances the DNA repair capacity of glioblastoma cells, thereby inducing radio resistance

Prostate Cancer Prostatic Dis 9(1):6876

10.1111/j.1582-4934.2008.00588.x J

Studies have indicated that prolonged or high-dose administration of ferroptosis inducers may result in arrhythmias and structural damage to cardiac tissue, thereby limiting their application in systemic treatment of solid tumors (143, 144)

Comparison of conventional dose versus superdose platelet-rich plasma for knee osteoarthritis: a prospective, triple-blind, randomized clinical trial