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Description

Non-enteric-coated preparations of VPA are rapidly and nearly completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring 14 hours after ingestion [12]

2011;343:d4002

2a), indicating that this effect is due to decreased activity of KGDDs

Considering the similarity between pyruvate-depletion induced dispersion and native dispersion, our findings suggest native dispersion to be linked to redox balancing or reductive stress, likely induced by pyruvate limiting conditions within the biofilm