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Pharmacol Rev 50:335356 Sipos K, Lange H, Fekete Z, Ullmann P, Lill R, Kispal G (2002) Maturation of cytosolic iron-sulfur proteins requires glutathione

Proteomic analyses showed upregulation of mitochondrial and antioxidant pathways, while FLIM indicated a progressive increase in enzyme-bound NAD(P)H, consistent with a shift toward oxidative metabolism

Several genes contribute to both susceptibility and progression of MASLD, with the most extensively studied genetic variants found in patatin-like phospholipase domain-containing 3 (PNPLA3), transmembrane 6 superfamily member 2 (TM6SF2), and membrane-bound O-acyltransferase domain-containing 7 (MBOAT7) [257]

LRRC8/VRAC anion channels are required for late stages of spermatid development in mice

10.1128/mBio.00285-12 212 WenX.LiuY.BaiY.LiM.FuQ.ZhengY