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Nevertheless, experiments have confirmed that WJMSCs can be induced to differentiate into CPCs and then transplanted in vivo, leading to not only an enhanced repair effect relative to WJMSC transplantation, but also avoidance of adverse consequences resulting from pluridirectional differentiation of stem cells as much as possible

V.VasconcellosR

As mentioned above, TAMs are major inflammatory cell populations that secrete a variety of inflammatory mediators, such as CCL2 and CXCL8, and maintain tumor proliferation and immunosuppressive phenotype by inducing the transformation of TAMs from pro-inflammatory M1 type to anti-inflammatory M2 type

Thus, the role of the axis identified here in NAFLD has not been directly tested

The Nrf2 Pathway and antioxidant activity Nuclear factor erythroid 2 [NF-E2]-related factor 2, known by the much easier to remember acronym Nrf2 is a transcription factor which is a major regulator of cell protection, including antioxidant, responses