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Intervention trials indicate that combined probiotic and prebiotic supplementation can significantly decrease TPOAb and TgAb concentrations, improve gut barrier integrity, and restore microbial diversity in HT patients (Liu et al

Effects of a single intra-articular injection of a microsphere formulation of triamcinolone acetonide on knee osteoarthritis pain

Although it is not possible to draw direct comparisons from the real-world evidence study and the RCTs, these examples demonstrate how reporting the treatment effect from different perspectives can provide a broader understanding of the weight loss that can be expected with a medication, and can be useful for clinicians when assessing pharmacotherapeutic options for their patients