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More specifically, GPX4 inhibits ferroptosis by reducing each PUFA-OOH to the corresponding PUFA-OH and oxidizing GSH (a reductive cofactor of GPX4) to GSSG (oxidized GSH) (Figure 1B) (Ma et al., 2022a)

Although the relevance of the present study to the human disease deserves further investigation, these findings may be useful to future studies using this model of colitis aimed to understand the pathophysiology of IBD

Harper, who in 1943 helped to establish that the gastro-intestinal hormone pancreozymin stimulated the secretion of pancreatic enzymes (Kieffer

However, COX-1 is expressed at some sites of inflammation

, through their strong abilities to bind such pollutants), relatively few studies about the role of Cys in these processes have been reported