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KD or BHB supplementation restored mitochondrial metabolism and immune function of CD4 + T cells, thereby reducing severe illness and mortality in mice during severe SARS-CoV-2 infection (Karagiannis et al., 2022)

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5.4 Associated effects of atherosclerosis comorbidities on neutrophil metabolism Neutrophils exhibit metabolic reprogramming during metabolic disorders such as obesity and T2DM as important comorbidities and risk factors of atherosclerosis and CVD