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Additionally, the composition of the intestinal microbiomes of the three groups was analyzed by determining the taxonomic similarity of the bacteria at the genus and phylum levels

[17] Concomitant use of topiramate also increases the risk of hepatic encephalopathy by 2 mechanisms: By blocking carbonic anhydrase and producing a degree of metabolic acidosis, which shifts the ammonium ion equilibrium towards ammonia

The question whether GABA forming microbiota can alter plasma GABA is unresolved: two germ-free models employing metabolomics support this premise (97, 98) whereas another germ-free rodent study did not (99)

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