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To prevent an infection, dont use any sharp implements to cut or push back your cuticles, and dont allow your manicurist to cut them, Rich advised

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Step 2 Membrane Binding and Insertion: Upon binding to membrane-localised HDM-2, PNC-27 inserts into the lipid bilayer via its C-terminal transmembrane-penetrating domain, anchoring the PNC-27HDM-2 complex within the cell membrane

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Cell (2011) 144:81023

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